What Are the Core and Non-Core Vaccines for Dogs and Cats?

Top 3 Takeaways – Core vs. Non-Core Vaccines

  • Core vaccines are essential for all pets, regardless of lifestyle, because they protect against widespread, often fatal diseases.
  • Non-core vaccines are optional and based on your pet’s risk profile, such as exposure to wildlife, boarding facilities, or travel.
  • At Bliss Animal Hospital, we customize every pet’s vaccine plan, ensuring they receive exactly what they need—no more, no less.

Introduction – Not All Pets Need the Same Shots

One of the most common questions we get from pet parents is: “What vaccines does my dog or cat really need?” It’s a great question—and the answer depends on a few factors: your pet’s age, lifestyle, environment, and overall health.

Vaccines fall into two main categories in veterinary medicine: core and non-core.

  • Core vaccines are considered essential for all dogs and cats.

  • Non-core vaccines are recommended selectively based on individual risk.

Understanding this distinction helps you make informed, confident decisions about your pet’s care—without over- or under-vaccinating.

What Are Core Vaccines?

Core vaccines protect against diseases that are:

  • Highly contagious

  • Widespread in the environment

  • Often fatal or have severe complications

  • Sometimes transmissible to humans (zoonotic)

Core Vaccines for Dogs

Vaccine Disease(s) Covered Why It’s Core
Rabies Rabies virus Fatal to both pets and humans; legally required in California
DHPP Distemper, Hepatitis (Adenovirus), Parvovirus, Parainfluenza Protects against four severe, highly contagious viruses common in all regions

Core Vaccines for Cats

Vaccine Disease(s) Covered Why It’s Core
Rabies Rabies virus Required in some cities; zoonotic and nearly always fatal
FVRCP Feline Viral Rhinotracheitis (Herpesvirus), Calicivirus, Panleukopenia Widespread in homes, shelters, and catteries; especially dangerous for kittens

Even indoor-only cats and dogs need these core vaccines, since exposure can still occur indirectly—through people, open windows, other pets, or unexpected escapes.

What Are Non-Core Vaccines?

Non-core vaccines are recommended only if your pet’s lifestyle, location, or activities increase their exposure to specific risks. These are not universally required but can be crucial for protection in certain environments.

At Bliss Animal Hospital, we determine non-core vaccine needs based on:

  • Where you live (e.g., near wooded areas or water)
  • Whether your pet boards, grooms, or goes to daycare
  • Outdoor access or travel history
  • Age and immune system status

Non-Core Vaccines for Dogs

Vaccine Disease(s) Covered Recommended If…
Leptospirosis Lepto bacteria (zoonotic) Your dog hikes, drinks from puddles, or lives near wildlife
Bordetella (Kennel Cough) Bordetella bronchiseptica Your dog visits grooming salons, daycare, or boarding facilities
Canine Influenza Dog flu virus Required by many boarding facilities or during outbreaks
Lyme Disease Tick-borne Borrelia Your dog hikes or travels to high-tick regions (e.g., Northeast, upper Midwest)

Non-Core Vaccines for Cats

Vaccine Disease(s) Covered Recommended If…
Feline Leukemia Virus (FeLV) Viral immune suppression, cancer risk Your cat goes outdoors or lives with other cats of unknown status
Bordetella (rare) Respiratory bacteria Only in crowded or high-risk shelter environments
Chlamydia felis Eye and respiratory infections Multi-cat homes or catteries with infection history

How We Decide What Your Pet Needs

There’s no single formula that fits every pet. At Bliss Animal Hospital, we begin every vaccine plan with:

  • A comprehensive lifestyle assessment

  • Your pet’s age, breed, and medical history

  • Any prior vaccine reactions or sensitivities

  • Plans for travel, boarding, or daycare

  • Your personal concerns about safety, frequency, and immunity

From there, we explain the role of each vaccine—what it protects against, how often it’s needed, and why it may or may not apply to your pet.

Can I Skip Non-Core Vaccines If I’m Careful?

Possibly—but it depends on your risk tolerance. Let’s take Leptospirosis as an example. It’s a bacterial disease carried by wildlife and spread through urine-contaminated water or soil. Dogs can contract it in parks or backyards with puddles. It’s also zoonotic, meaning humans can get it too.

If your dog lives in Lake Forest, hikes locally, or drinks from standing water, we’ll likely recommend the vaccine—even if they don’t leave town.

Bottom line: we’re not just protecting your pet—we’re also protecting your family and community.

What If My Pet Had a Reaction Before?

We take adverse events very seriously. If your pet has had a prior reaction—even mild swelling or lethargy—we’ll:

  • Space out vaccines

  • Pre-treat with antihistamines

  • Avoid certain brands or adjuvants

  • Consider antibody titer testing to evaluate immunity without immediate re-vaccination

Our goal is to provide maximum protection with minimum risk.

Titer Testing: An Option for Some Core Vaccines

For core vaccines like distemper, parvo, and panleukopenia, we can sometimes use titer testing to check antibody levels. This helps us decide whether a booster is necessary, especially in pets with vaccine sensitivity.

However, rabies cannot be skipped or replaced by titers due to public health law.

Conclusion – Smarter Vaccination Starts with Personalization

Not every pet needs every vaccine—but every pet does need a personalized vaccination plan.
At Bliss Animal Hospital, we help you understand what’s required, what’s optional, and what’s truly beneficial based on your pet’s health and lifestyle.

By separating core and non-core vaccines, we focus on what matters most: keeping your pet safe, healthy, and protected—without unnecessary shots.

Ready to Build a Custom Vaccine Plan for Your Pet?

Our veterinary team is here to help. Book a visit or consultation today.
Schedule Online or call (949) 354-5201

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The blissfull faces behind the care

Driven by compassion and purpose, here is the team who will work to make a difference in your pet’s life. Every single visit.

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Dr. Nayara Pataro

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Dr. Sam Amirshahi

Veterinarian

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What your neighbors are saying!

Areas we Serve at Bliss Animal Hospital:

“Better Care. Better medicine.” This is our motto, and our veterinary staff stands behind it.
Bliss Animal Hospital is conveniently located at the Home Depot Plaza in Foothill Ranch, less than a 10-minute drive from the neighborhoods of Lake Forest, Rancho Santa Margarita, Mission Viejo, and Irvine (Great Park and Portola Springs). We also serve more distant regions like Tustin, Coto de Caza, Las Flores, Ladera Ranch, Laguna Hills, Laguna Woods, Stonegate (Irvine), Woodbury (Irvine), and Cypress Village (Irvine).

Our vet hospital is ready to serve not only the communities of South Orange County but also anyone who truly believes that veterinary medicine starts with relationships.